Dr Obinna Ekwunife is a pharmacist and a public health scientist. He is a senior lecturer in the Department of Clinical Pharmacy and Pharmacy Management, Nnamdi Azikiwe University, Nigeria. He coordinates the Research Group for Evidence-Based Health Care in Nnamdi Azikiwe University (www.ebhc-unizik.com). His research focuses on establishing optimal and efficient use of pharmaceuticals and health technologies applying pharmacoeconomics and evidence-based medicine research methods. He is also interested in health service research and clinical trials. He has over 30 publications in international scientific journals and is a member of a number of scientific organisations including Nigerian Young Academy (NYA) and African Research Network for Neglected Tropical Diseases (ARNDT). He has won some grants including the Georg Forster Research Fellowship (Alexander von Humboldt Foundation) and EDCTP Career Development Fellowship.Interest Includes: Pharmacoeconomics, Pharmacoepidemiology, Evidence-based medicine/public health, Health service research
Undergraduate Qualifications
Postgraduate Qualifications
M.Pharm, PhD
Books Published
1. Obinna Ekwunife. Pharmaceutical Care Program in a Nigerian Pharmacy: Effect on blood pressure and quality of life. Lambert Academic Publishing AG & Co. KG, Saarbrucken, Germany. 2010
2. Obinna Ekwunife. Cost Effectiveness Analysis of Interventions to Control High BP in Nigeria. Scholars’ Press, Germany. 2014. ISBN 978-3-639-70648-2

1. Isah AUJ, Ekwunife OI, Ejie IL, Mandrik O.Effects of nutritional supplements on the re-infection rate of soil-transmitted helminths in school-age children: A systematic review and meta-analysis. PLoS One. 2020 Aug 13;15(8):e0237112. doi: 10.1371/journal.pone.0237112.

2. Akunne MO, Okonta MJ, Ukwe CV, Heise TL, Ekwunife OI. Satisfaction of Nigerian patients with health services: a protocol for a systematic review. Syst Rev. 2019 Nov 1;8(1):256. doi: 10.1186/s13643-019-1160-z.

3. Mandrik O, Ekwunife OI, Meheus F, Severens JLH, Lhachimi S, Uyl-de Groot CA, Murillo R. Systematic reviews as a "lens of evidence": Determinants of cost-effectiveness of breast cancer screening. Cancer Med. 2019 Sep 30. doi: 10.1002/cam4.2498.

4. Oli AN, Akunna PE, Ekwunife OI, Okoye EL, Anyaoku CS, Ibeanu GC, Obi E, Ihekwereme CP, Objai M. Pleurotus ostreatus extract enhances the phagocytic actions of neutrophils agains Streptococcus pneumoniae. Annals of Medical and Health Sciences Research. 2019;9:499-508

5. Ekwunife OI, Anetoh MU, Kalu SO, Ele PU, Eleje GU. Conditional economic incentives and motivational interviewing to improve adolescents' retention in HIV care and adherence to antiretroviral therapy in Southeast Nigeria: study protocol for a cluster randomised trial. Trials. 2018 Dec 29;19(1):710. doi: 10.1186/s13063-018-3095-4.

6. Okafor CE, Ekwunife OI. Cost-effectiveness analysis of diarrhoea management approaches in Nigeria: A decision analytical model. PLoS Negl Trop Dis. 2017 Dec 19;11(12):e0006124. doi: 10.1371/journal.pntd.0006124. eCollection 2017 Dec.

7. Ekwunife OI, Lhachimi SK. Cost-effectiveness of Human Papilloma Virus (HPV) vaccination in Nigeria: a decision analysis using pragmatic parameter estimates for cost and programme coverage. BMC Health Serv Res. 2017 Dec 8;17(1):815. doi: 10.1186/s12913-017-2758-2.

8. Anyakora C., Ekwunife O., Alozie F., Esuga M., Ukwuru J., Onya S., Nwokike J. Cost benefit of investment on quality in pharmaceutical manufacturing: WHO GMP pre- and post- certification of a Nigerian pharmaceutical manufacturer. BMC Health Services Research (2017) 17:665 DOI 10.1186/s12913-017-2610-8

9. Mandrik O, Ekwunife OI, Zielonke N, Meheus F, Severens JL, Lhachimi SK, Murillo R. What determines the effects and costs of breast cancer screening? A protocol of a systematic review of reviews. Syst Rev. 2017 Jun 28;6(1):122. doi: 10.1186/s13643-017-0510-y.

10. Sweiti H, Ekwunife O, Jaschinski T, Lhachimi SK. Repurposed therapeutic agents targeting the Ebola virus: a systematic review. Current therapeutic Research (Accepted, January 2017). DOI: http://dx.doi.org/10.1016/j.curtheres.2017.01.007
11. Ezennia IJ, Nduka SO, Ekwunife OI. Cost benefit analysis of malaria rapid diagnostic test: the perspective of Nigerian community pharmacists. Malaria Journal. 2017 Jan 3;16(1):7. doi: 10.1186/s12936-016-1648-0.

12. Khan Z, Khan S, Christianson L, Rehman S, Ekwunife O, Samkange-Zeeb F. Smokeless tobacco and oral potentially malignant disorders in South Asia: a systematic review and meta-analysis. Nicotine Tobacco Research. 2016 Dec 7. pii: ntw310.

13. Ekwunife OI, O'Mahony JF, Gerber Grote A, Mosch C, Paeck T, Lhachimi SK. Challenges in Cost-Effectiveness Analysis Modelling of HPV Vaccines in Low- and Middle-Income Countries: A Systematic Review and Practice Recommendations. Pharmacoeconomics. 2016 Sep 16.

14. Khan Z, Khan S, Christianson L, Rehman S, Ekwunife O, Samkange-Zeeb F. Smokeless tobacco and oral potentially malignant disorders in South Asia: a protocol for a systematic review. Systematic Review. 2016 Aug 24;5(1):142. doi: 10.1186/s13643-016-0320-7.

15. Umeh BI, Nduka SO, Ekwunife OI. Mothers' Willingness to Pay for HPV Vaccines in Anambra State, Nigeria: A Cross Sectional Contingent Valuation Study. Cost Effectiveness and Resource Allocation. 2016 Jun 6;14:8. doi: 10.1186/s12962-016-0057-0.

16. Ekwunife OI, Ezenduka CC, Uzoma BE. Evaluating the sensitivity of EQ-5D in a sample of patients with type 2 diabetes mellitus in two tertiary health care facilities in Nigeria. BMC Research Notes 2016;9:24 doi:10.1186/s13104-015-1832-2

17. Offu O, Anetoh M, Okonta M, Ekwunife O. Engaging Nigerian community pharmacists in public health programs: assessment of their knowledge, attitude and practice in Enugu metropolis. Journal of Pharmaceutical Policy and Practice. 2015 Nov 9;8:27. doi: 10.1186/s40545-015-0048-0. eCollection 2015

18. Sweiti H, Ekwunife O, Jaschinski T, Lhachimi SK. Repurposed therapeutic agents targeting the Ebola virus: a protocol for a systematic review. Systematic Reviews. 2015 Nov 25;4(1):171. doi: 10.1186/s13643-015-0153-9.

19. Ekwunife OI, Gerber Grote A, Mosch C, O’Mahony JF, Lhachimi SK. Assessing cost-effectiveness of HPV vaccines with decision analytic models: what are the distinct challenges of low- and middle-income countries? A protocol for a systematic review. Systematic Reviews 2015, 4:68 doi:10.1186/s13643-015-0057-8

20. Oreh CN, Ekwunife OI. Ignorance about Chlamydia compared to gonorrhoea infection among sexually active people in Nigeria. International Journal of Health Promotion and Education. 2015. DOI: 10.1080/14635240.2015.1016622.

21. Okoye MO, Ukwe VC, Okoye TC, Adibe MO, Ekwunife OI. Satisfaction of HIV patients with pharmaceutical services in South Eastern Nigerian hospitals. International Journal of Clinical Pharmacy. 2014 Oct;36(5):914-21. doi: 10.1007/s11096-014-0006-y. Epub 2014 Sep 7.

22. Ezenduka CC, Ogbonna BO, Ekwunife OI, Okonta MJ, Esimone CO. Drugs use pattern for uncomplicated malarial in medicine retail outlets of Enugu urban, southeast Nigeria: implications for malaria treatment policy. Malaria Journal. 2014 Jun 24;13(1):243.

23. Ekwunife OI, Aguwa CN. Cost-effectiveness analysis of interventions to improve control of high blood pressure in low resource settings: the case of Nigeria. Cardiology and Angiology: The International Journal. 2014;2(2):DOI : 10.9734/CA/2014/10292

24. Okafor CE, Ekwunife OI. Self-reported adherence to antiretroviral therapy in sub-Saharan Africa: A meta-analysis. International Journal of Public Health and Epidemiology 2014, 3(3):17-25
25. Oreh NC, Esimone CO, Ekwunife OI. Prevalence and susceptibility patterns of clinical isolates of Escherichia coli to various antimicrobials in a clinical microbiology laboratory in South-south Nigeria. African Journal of Clinical and Experimental Microbiology 2013, 14(1): 23-28

26. Ekwunife OI, Okafor CE, Ezenduka CC and Udeogaranya PO. Cost-utility analysis of antihypertensive medications in Nigeria: a decision analysis. Cost Effectiveness and Resource Allocation 2013, 11:2
27. Ekwunife OI, Aguwa CN, Igboeli NU. Health Utilities Index Mark 3 (HUI3) demonstrated construct validity in a Nigerian population with hypertension. Health and Quality of Life Outcomes, 2013 Mar;22(2):455-8. doi: 10.1007/s11136-012-0150-6. Epub 2012 Mar 11.
28. Ubaka CM, Ekwunife OI, Adibe MO. Does the clinical clerkship course improve students' attitudes towards pharmaceutical care? International Journal of Pharmacy Practice. 2012 Aug;20(4):272-4. doi: 10.1111/j.2042-7174.2012.00191.x. Epub 2012 Feb 28.
29. Ekwunife OI, Oreh C, Ubaka CM. Concurrent use of complementary and alternative medicine with antiretroviral therapy reduces adherence to HIV medications. International Journal of Pharmacy Practice. 2012 Oct;20(5):340-3. doi: 10.1111/j.2042-7174.2012.00204.x. Epub 2012 Apr 4.
30. Njilele AC, Ukwe CV, Okonta JM, Ekwunife OI. Development of a patient satisfaction questionnaire for HIV/AIDS patients in Nigeria. International Journal of Clinical Pharmacy. 2011. DOI 10.1007/s11096-011-9596-9

31. Ekwunife OI, Aguwa CN, Adibe MO, Barikpoar E, Onwuka C. Health state utilities of a population of Nigerian hypertensive patients. BMC Research Notes 2011, 4:528

32. Ekwunife OI, Aguwa CN. A meta analysis of prevalence rate of hypertension in Nigerian populations. Journal of Public Health and Epidemiology 2011: 3(13):604-607
33. Ekwunife OI, Ubaka CM. Drug utilization review of antihypertensive therapy among patients with compelling indications in two hospital in South-Eastern Nigeria. Journal of Pharmacy and Pharmacological Research 2011, 2(1):25-28.
34. Ukwe CV, Ekwunife OI, Ayogu E and Adibe MO. Cost-effectiveness study of Artemether-lumefantrine, artesunate-amodiaquine and dihydoartemisinin-piperaquine in the treatment of uncomplicated malaria in a Nigerian Hospital. Drug Invention Today 2010, 2(10),429-432
35. Igboeli NU, Ukwe CV, Ekwunife OI. Increasing use of artemisinin-based combination therapy for treatment of malaria infection in Nigerian hospitals. Pharmacy Practice (Internet) 2010 Oct-Dec;8(4):243-249.
36. Ukwe CV, Ekwunife OI, Epueke EA, Ubaka CM. Antimalarial Activity of Ageratum conyzoides in combination with Chloroquine and Artesunate. Asian Pacific Journal of Tropical Medicine 2010:412-420
37. Ekwunife OI, Udeogaranya PO, Nwatu IL. Prevalence, awareness, treatment and control of hypertension in a Nigerian population. Health 2010;2(7):731-735. doi:10.4236/health.2010.27111.
38. Ukwe CV, Epueke EA, Ekwunife OI, Okoye TC, Akudor GC, Ubaka CM. Antimalarial activity of aqueous extract and fractions of leaves of Ageratum conyzoides in mice infected with Plasmodium berghei. International Journal of Pharmaceutical Sciences, Vol.2 (1), 2010, 33-38.
39. Ukwe CV, Ekwunife OI, Ubaka CM. Pattern of Antimalarial Drug-use for the Treatment of Hospitalized Pregnant Women in South-Eastern Nigeria. International Journal of Pharmagenesis 1(2), July-December 2010, pp. 279-28.
40. Ekwunife OI, Ukwe CV, Awanye AM. Knowledge and treatment seeking pattern of malaria infection in Abakaliki, Ebonyi State. Research Journal of Pharmaceutical, Biological and Chemical Sciences. 2010;1(2):317-323.
41. Ekwunife OI, Udeogaranya PO, Adibe MO. Predictors of self reported adherence to antihypertensive medication in a Nigerian Population. Journal of Basic and Clinical Pharmacy 2010;1(2):133-138.
42. Ukwe CV, Ekwunife OI, Udeogaranya PO, Iwuamadi UI. Self-reported adherence to HAART in south-eastern Nigeria is related to patients’ use of pill box. Journal of Social Aspects of HIV/AIDS. 2010;7(1):94-99.
43. Oyim EK, Ibezim EC, Okoye TC, Esimone CO, Brown SA, Ekwunife OI. In-vivo studies on the bioequivalence of some brands of Ofloxacin and levo-floxacin tablets marketed in Nigeria. International Journal of drug development and Research 2009;1(1):110-116.
44. Ukwe CV, Udeogaranya PO, Ekwunife OI. Pharmacoeconomic comparison of treatments for the eradication of Helicobacter Pylori in Enugu State, Nigeria. Journal of Pharmaceutical Research. Vol.8, No.3, July 2009.
45. Udeogaranya PO, Ukwe CV, Ekwunife OI. Assessment of attitudes of University of Nigeria Pharmacy Students toward pharmaceutical care. Pharmacy Practice (Internet) 2009 7(3).
46. Adibe MO, Ukwe CV, Ekwunife OI. Evaluation of therapeutic uses of aloe barbadensis miller (aloe Vera) plant among staff and students in a Nigerian university. International Journal of Pharmaceutical Sciences, May-August 2009; 1(1):59-70
47. Aguwa CN, Ukwe CV, Ekwunife OI. Effects of Pharmaceutical care programme on blood pressure and quality of life in a Nigerian Pharmacy. International Journal of Clinical Pharmacy. 2008:30;107-110.
48. Ukwe CV, Ekwunife OI. Drug Utilisation Study of antimalarials for the treatment of hosptialized children under five in South-Eastern Nigeria. Pharmacoepidemiology and Drug Safety. 2008:17;1-6.
49. Okonta JM, Momoh MA, Ekwunife OI, Mbagwu ISU, Abali S. Assessment of HIV/AIDS Awareness and Changing of Sexual Practices among Secondary School Students in Nsukka Environment. Tropical Doctor. 2007:37;269-271.
Previous Employment
1. Lecturer I - University of Nigeria Nsukka
2. Postdoctoral fellow - University of Bremen, Germany/Institute for Preventive Research and Epidemiology - BIP